Evasion of innate immunity by poxviruses
14:00
Talk & Lecture
1
3155687
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2026-04-24
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Speaker: Geoffrey SmithVenue: Lecture Hall, Floor 1, School of Medicine, Zijingang CampusAbstract: Professor Geoffrey Smith earned his PhD in 1981 at the laboratory of Alan Hay at the National Institute for Medical Research, London, UK (the predecessor of the Francis Crick Institute), focusing on the replication mechanism of influenza virus. Between 1981 and 1984, he conducted postdoctoral research at the laboratory of Bernard Moss at the National Institutes of Health (NIH) in the United States. During this period, he pioneered the development of recombinant vaccine technology using vaccinia virus (the smallpox vaccine) as a vector, proposing the original theory of using genetic engineering to modify viruses as recombinant vaccines. This principle has since been widely applied to the development of vaccines against various viruses and microorganisms. Professor Smith was elected a Fellow of the Royal Society in 2003 and a Member of the German National Academy of Sciences Leopoldina in 2011.Professor Smith has served as Professor of Pathogen Microbiology at the University of Oxford, Head of the Department of Virology at Imperial College London, and Head of the Division of Pathology at the University of Cambridge. In 2023, he returned to the Centre for Molecular Pathology at the University of Oxford to continue his research. In 2025, he joined the Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences. He currently serves as Chief Scientist of the Vaccine Research Center at the Shanghai Institute of Materia Medica, Chinese Academy of Sciences, and is Emeritus Professor at the Centre for Molecular Pathology, University of Oxford. His team’s main research directions include the interaction between poxviruses and host cells, the development of novel vaccines, and oncolytic viruses.
Professor Geoffrey Smith earned his PhD in 1981 at the laboratory of Alan Hay at the National Institute for Medical Research, London, UK (the predecessor of the Francis Crick Institute), focusing on the replication mechanism of influenza virus. Between 1981 and 1984, he conducted postdoctoral research at the laboratory of Bernard Moss at the National Institutes of Health (NIH) in the United States.
Geoffrey SMITH
2026-04-28 14:00:00
Zijingang Campus
From global governance 1.0 to global governance 2.0: from progress to precarity
15:30
Talk & Lecture
2
3155678
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2026-04-24
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Speaker: Michael BarnettVenue: Room 901, Department of Public Affairs, Zijingang CampusAbstract: Global governance was first coined in the early and optimistic days following the end of the Cold War. Capitalizing on an ending to the Cold War no one expected, the international community experienced thoughts of new beginnings and possibilities. Confrontation and fear would now yield to cooperation and optimism. The world began building and expanding existing multilateral organizations to produce not only mutual gains but also a sense of global community. Around the turn of the century, though world order began to darken and notions of progress began to replace precarity. The drivers of the new worldview has led to a new round of global governance defined by precarity, uncertainty, and risk. What kinds of global institutions can and will be built in this new world order?
Global governance was first coined in the early and optimistic days following the end of the Cold War. Capitalizing on an ending to the Cold War no one expected, the international community experienced thoughts of new beginnings and possibilities. Confrontation and fear would now yield to cooperation and optimism.
Michael BARNETT
2026-04-29 15:30:00
Zijingang Campus
Constructing temporal legitimacy under historical scarcity
10:00
Talk & Lecture
3
3149844
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2026-04-10
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Speaker: Dr. Jeremy ArolesVenue: Room A723, School of Management Building, Zijingang CampusAbstract: Organizations in nascent categories face a distinctive legitimation challenge as they must establish temporal credibility – a persuasive account of where they came from and where they are going – when both the organisational past and the sector’s direction are unsettled. Existing research on uses of the past has primarily examined organisations with rich temporal resources; we know less about how temporal legitimation works when the past itself must be constructed rather than curated. We ask: How do actors in nascent organisational categories construct temporal legitimacy when the temporal resources available to them are scarce? We address this question through a qualitative study of coworking spaces across four global cities, through which we identify five temporal legitimation strategies operating under two interdependent mechanisms: constructing temporal ground (manufacturing a credible past) and claiming temporal trajectory (naturalising a credible future). We theorise these as forming an iterative cycle in which constructed depth makes trajectory claims credible, while projected futures redefine which pasts are usable. We contribute to research on legitimation in nascent categories by theorising temporal legitimation as a distinct mechanism of category construction, and to the uses-of-the-past literature by showing how temporal work operates under conditions of historical scarcity.
Jeremy Aroles is an Associate Professor in Organization Studies. He joined the School for Business and Society at the University of York in December 2021, where he currently serves as Deputy Dean. Prior to this, he held academic positions at Durham University and the University of Manchester, where he earned his PhD in 2016.
AROLES Jeremy
2026-04-15 10:00:00
Zijingang Campus
AI is much smarter than humans (and so are pigeons, by the way)
9:30
Talk & Lecture
4
3149843
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2026-04-10
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Speaker: Max M. LouwerseVenue: Room 415, Haina Building 3, Zijingang CampusAbstract: Opportunities and threats of AI are abundant: “AI might be as smart as humans”, “Artificial General Intelligence is projected to occur in 2026”. But how intelligent is AI really, and how do we compare it to human intelligence? Why does it seem common to compare AI with human intelligence, but is it awkward and questionable to compare your intelligence with the intelligence of somebody else? This presentation argues that AI and psychology are heavily intertwined historically, terminologically and conceptually. It shows evidence for this both theoretically and practically in a range of research projects. It will take you on a journey of AI that turns out to be different than the one often portrayed in the media. One that covers intelligence, misconceptions, and pigeons.
Prof. Louwerse worked for almost 20 years in both in the UK and the US, authored over 200 scientific publications in computational and psycholinguistics, virtual reality, embodied cognition, and educational technologies. He holds two patents, and acquired €50M in research funding. Louwerse is a blogger for Psychology Today, and is author of the popular science books “Keeping those words in mind: How language creates meaning” and “Understanding human and artificial minds.”
LOUWERSE Max M.
2026-04-22 09:30:00
Zijingang Campus
Learning to Solve PDEs: Scientific Machine Learning from Principles to Practice
14:15
Talk & Lecture
5
3149840
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2026-04-10
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Speaker: Minseok ChoiVenue: Room 102, Haina Building 2, Zijingang CampusAbstract: Scientific Machine Learning (SML) is rapidly emerging as a powerful paradigm for addressing complex problems in science and engineering by integrating machine learning with real-world data and the fundamental laws of physics. This talk will provide a concise overview of the core concepts and algorithmic foundations of SML. In particular, it will introduce methodologies such as Physics-Informed Neural Networks (PINNs), which incorporate physical constraints directly into the learning process, and Operator Learning, which seeks to learn mappings between function spaces and thereby enables fast and efficient prediction of system responses under varying input conditions. The talk will also discuss recent developments aimed at overcoming key limitations of early PINN and operator learning approaches, including issues of long-time integration, data efficiency, generalization, and computational stability. Finally, several examples will be presented to illustrate how SML can lead to innovative and effective solutions in practical applications, often providing substantial speed-ups over traditional numerical simulations.
Minseok Choi received his B.S. and M.S. degrees from Seoul National University, South Korea, and his Ph.D. in Applied Mathematics from Brown University, USA. After completing his Ph.D., he worked as a Postdoctoral Researcher at Princeton University before joining Pohang University of Science and Technology (POSTECH), where he is currently an Associate Professor of Mathematics.
CHOI Minseok
2026-04-14 14:15:00
Zijingang Campus
Two sides of Hidden City Ticketing: analysis of a choice-based network revenue management model
14:30
Talk & Lecture
6
3149819
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2026-04-10
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Speaker:Nanxi ZhangVenue: Room 426, School of Economics Building, Zijingang CampusAbstract: "Hidden City Ticketing" (HCT) is a strategy where customers book flights with layovers at their intended destinations and skip the final leg of the journey. Empirical studies on airfare data have shown that HCT chances are very prevalent (about 15%-25%) in airline pricing. In this paper, we investigate the impact of HCT on airline revenue and discuss if the airline should eliminate all HCT chances from its price to achieve higher profit. We use a choice-based network revenue management model to characterize the airline’s dynamic pricing problem. As airlines may penalize customers who purchase HCT by canceling frequent flyer miles and banning future travel with the airline, we capture customers’ concerns about the risks of HCT through a choice model. Our analysis shows that adjusting prices to completely eliminate HCT chances may overly constrain the pricing strategy, and it harms the airline revenue more than customers’ HCT purchase behavior. Furthermore, the impact of HCT is two-sided: While HCT can erode the airline’s revenue, it can also boost revenue in some cases. In the worst case, if customers purchase HCT, the airline’s revenue can be half of what it would be if customers don’t purchase HCT. In the best case, the airline’s revenue in the case customers purchase HCT can be twice that of the case where customers do not purchase HCT. Furthermore, the worst-case and best-case revenue bounds are both tight.
Before joining Ivey, Nanxi received her PhD from Shanghai University of Finance and Economics under the supervision of Professor Bo Jiang. During her PhD, she was a visiting PhD student at Sauder Business School, UBC advised by Professor Chris Ryan. After graduation, she visited Professor Zizhuo Wang at Chinese University of Hong Kong, Shenzhen from July 2023 to Dec 2023. Her current research lies in revenue management, data-supported decision making and contract theory.
ZHANG Nanxi
2026-04-15 14:30:00
Zijingang Campus
The coming golden age of human immunology
12:00
Talk & Lecture
7
3149809
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2026-04-10
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Speaker: Mark M. DavisVenue: Lecture Hall 2A-203, International CampusAbstract: The human immune system is likely far more complex than that of inbred mice, necessitating fully human experimental systems to test hypotheses about novel immune mechanisms. To this end, we have developed functional human immune organoids from discarded tonsils and spleens. These organoids mount specific T and B cell responses to vaccines and are amenable to CRISPR-based genetic manipulation (Wagar et al., Nat. Medicine 2021). By knocking out FoxP3 and Granzyme B, we demonstrated distinct roles for CD4 and CD8 regulatory T cells in controlling autoimmunity and showed that disabling CD4 Tregs markedly enhanced flu-specific antibody affinity (Chen, Ghanizada et al., Nat. Immunol. 2025). We also showed that supplementing T cell help to disfavored flu strains substantially boosts antibody responses (Mallajoysula et al., Science 2024). Ongoing work with spleen organoids reveals a broader cellular diversity and improved vaccine responsiveness compared to tonsils. Combining spleens with skin or lung organoids from the same donor further enables reconstruction of classical immune interactions relevant to infectious disease. While still early, this approach holds considerable promise for discovering human-specific immune mechanisms with the advantages of an in vitro system.
The human immune system is likely far more complex than that of inbred mice, necessitating fully human experimental systems to test hypotheses about novel immune mechanisms. To this end, we have developed functional human immune organoids from discarded tonsils and spleens.
DAVIS Mark M.
2026-04-16 12:00:00
International Campus
Geometric representations of projective spaces and generalized quadrangles
9:30
Talk & Lecture
8
3147855
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2026-04-03
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Speaker: Koen ThasVenue: Room 203, Haina Building 2 , Zijingang CampusAbstract:(1) Title: Geometric representations of projective linesAbstract: Given a division ring B and a division ring A such that the left dimension [A : B] = 2, one naturally has a projective line PG(1,B) at one’s disposal. If one considers a (left) vector space V of dimension n over A, a representation of PG(1,B) arises as a spread in PG(2n - 1,B). In this lecture, we study special “twisted” representations in the case n = 2 with remarkable geometric and automorphic properties. (This is joint work with Hendrik Van Maldeghem.)(2) Title: Modular representation theory of skew translation generalized quadranglesAbstract:Suppose Q is a skew translation generalized quadrangle (STGQ) with associated central symmetry group S. In a recent paper, we have shown that S cannot be a subgroup of (ℤ,+) (whereas in the finite case, one indeed has examples of STGQs for which the central symmetry group is cyclic). More generally, call an STGQ modular if Aut(S) is a subgroup of the modular group GL(n,ℤ). In the current lecture, we present new nonexistence results for modular STGQs. (3) Title: Free automorphic actions on projective spacesAbstract:The theory of Singer groups has been very fruitful in finite geometry over the years, but lacks the proper foundations in the infinite case. (Recall that a Singer group of a projective space is an automorphism group which acts sharply transitively on the point set.) The standard formalism to construct Singer groups for a projective space PG(n,K) (with K a field and infinite) consists of taking a field extension E of K degree n + 1, and interpreting E as an (n + 1)-dimensional vector space over K. The field E then naturally acts freely and transitively on the points of PG(n,K) by multiplication. But what happens if there are no field extensions of degree n + 1 (and in particular if K is algebraically closed)? This is the question we want to explore in the present lecture.
Given a division ring B and a division ring A such that the left dimension [A : B] = 2, one naturally has a projective line PG(1,B) at one’s disposal. If one considers a (left) vector space V of dimension n over A, a representation of PG(1,B) arises as a spread in PG(2n - 1,B). In this lecture, we study special “twisted” representations in the case n = 2 with remarkable geometric and automorphic properties. (This is joint work with Hendrik Van Maldeghem.)
THAS Koen
2026-04-10 09:30:00
Zijingang Campus
Geotechnical engineering for sustainable social development
15:00
Talk & Lecture
9
3144915
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2026-03-27
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Speaker: Lidija ZdravkovicVenue: Anzhong Lecture Hall, Anzhong Building, Zijingang CampusAbstract: Professor Lidija Zdravkovic is a Professor of Computational Geomechanics at Imperial College London. She served as Head of the Geotechnics Section from 2014 to 2024, and currently holds the positions of Admissions Tutor for the MSc in Geotechnical Engineering and Co-Director of the Nuclear Engineering Centre at the same institution. She also serves as Editor-in-Chief of the internationally renowned journal Géotechnique. Her research focuses on the development and application of numerical methods in geotechnical engineering, as well as the experimental characterization of soils under mechanical and thermal disturbances. Her major contributions include the development of computational algorithms and constitutive models for coupled thermo-hydro-mechanical-chemical analysis of saturated and unsaturated soils under static and dynamic conditions, and their successful application to complex soil-structure interaction problems. These applications span offshore foundations, life-cycle assessment of climate change-affected infrastructure (such as embankments, earth dams, and slopes), flood defense works, rapid landslides, tunnels and deep excavations, as well as geological disposal of nuclear waste. Her core research philosophy is to provide reliable computational predictive tools for geotechnical engineering design through the deep integration of laboratory/field soil characterization and advanced numerical simulation. To date, Professor Zdravkovic has supervised over 40 doctoral students. In 2019, she was awarded the Imperial College President’s Medal for Excellence in Teaching and Research Supervision. She has published over 250 scientific papers and co-authored the classic textbook Finite Element Analysis in Geotechnical Engineering (two volumes), the Chinese edition of which was introduced by Science Press in 2010. Her research achievements have received numerous accolades, including the Telford Gold Medal from the Institution of Civil Engineers (2002), and the British Geotechnical Association Medal (2008/2010/2012/2020). She was also invited to deliver the Géotechnique Lecture in 2013 and the Rankine Lecture in 2024, one of the highest honors in the field of geotechnical engineering.
Professor Lidija Zdravkovic is a Professor of Computational Geomechanics at Imperial College London. She served as Head of the Geotechnics Section from 2014 to 2024, and currently holds the positions of Admissions Tutor for the MSc in Geotechnical Engineering and Co-Director of the Nuclear Engineering Centre at the same institution.
ZDRAVKOVIC Lidija
2026-03-28 15:00:00
Zijingang Campus