New method for enhanced osseointegration of metal implants
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2604903
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2022-07-19
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The guided endogenous mesenchymal stem cells recruitment and angiogenesis through bone implants surface modification are the most essential for proper bone regeneration and enhanced osseointegration. However, most reported studies were conducted to endow implant surface with multiple functionalities via multiple bio-active compounds and complicated strategies. Moreover, our understanding of the regulatory mechanism of surface coatings for vascularization and osteogenesis liaison is incomplete, e...
Nano-enabled way discovered to control rice bacterial leaf blight disease
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2022-07-19
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The bacterial leaf blight disease (BLB) is among the three most devastating pathogens limiting rice production in China. Recent years has witnessed a resurgence of BLB in Zhejiang and other major rice areas in China due to climate change and the changes in the cultivation system. Moreover, there has emerged a new epidemic pattern. These have posed great challenges to the control of BLB. As one of the ten emerging chemical technologies that will change the world in the future, nano-enabled agroch...
ZJU scientists identify cell-fate regulatory programs using single-cell atlas of mouse development
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2022-07-18
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The robustness of the developmental process for multicellular organisms suggests a dedicated regulatory program that governs the trajectories of cell-fate decisions. According to Waddington’s epigenetic landscape theory, differentiated cell types arise from an unstable stem / progenitor state and eventually fall into stable cell-fate attractors. The emerging concept of the state manifold derived from single-cell data has further enhanced our understanding of lineage progression. What are the ge...
ZJU scientists unravel how SUMOylation coordinates endothelial angiogenic signaling
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2022-07-17
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The vascular network is the primary system for transporting nutrients, oxygen and metabolites. Therefore, angiogenesis, the formation of new blood vessels from pre-existing vessels, is of vital importance to the function of organisms. At the core of angiogenesis are endothelial sprouting and lumen formation. The basic fibroblast growth factor (FGF2) has been recognized as the first proangiogenic molecule, and it facilitates angiogenesis by activating FGF receptor 1 (FGFR1) signaling in endotheli...
ZJU Green Origin Association wins UN PRME Award
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2022-07-10
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On June 4, the Green Origin Association (GOA) of Zhejiang University received the 2022 PRME Student Recognition Award for excellence in SDG impact. Winning the award out of 300+ student associations worldwide is a welcomed recognition of their excellent performance advancing sustainability practices and responsible management education at ZJU.During the Award Ceremony, PRME officials introduced the outstanding achievements of the GOA in practicing environmental protection in the past year: over ...
Solving the mystery of ultralow-voltage LEDs
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2601333
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2022-07-05
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Light-emitting diodes (LEDs) have created far-reaching impacts on display and lighting industries. For a LED to emit light, the minimum voltage is widely considered to be equal to the bandgap voltage of the material, in consideration of the energy conservation principle. Reducing the operating voltages of LEDs can save power and improve speed.In recent years, light emission at sub-bandgap voltages (typically 80-100% of the bandgaps) was observed for some emerging classes of LEDs, including organ...
Genius translator's vision restored at SAHZU
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2022-07-05
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Left to right: Prof. XU Wen, JIN Xiaoyu, JIN Xingyong (Xiaoyu's Father), HUANG Lina (community worker), Dr. CHEN BinbinA special patient arrived at the Eye Center of the Second Affiliated Hospital, Zhejiang University School of Medicine (SAHZU) on June 24, and had a new contact lens.The patient is Mr. JIN Xiaoyu, the genius translator whose story swept the whole country five months ago and touched millions of Chinese readers. (Click to learn about his story)Mr. Jin received a surge...
International joint research reveals the efficacy of acupoint hot compress on postpartum recovery
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2022-07-03
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The postpartum period, especially the first few weeks after childbirth, could be a challenging time for mothers, as they experience adjustments to life with newborns, as well as discomfort and stress brought by postpartum urinary retention, contraction pain, breastfeeding concerns and other puerperal complications. Postpartum care is very significant to promote lifelong physical and psychological well-being of mothers and newborns.Acupoint hot compress, with a combination of acupoints and natura...
Zhejiang University and government of Aichi Prefecture sign MoU online
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2022-07-02
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On June 30, WU Zhaohui, president of Zhejiang University, and Hideaki Omura, governor of Aichi Prefecture, signed a MoU on cooperation and exchange. HE Lianzhen, vice president of Zhejiang University, attended the MoU-signing ceremony and delivered closing remarks. Also present at the ceremony were CAE Fellow ZHENG Jingyang from the College of Energy Engineering, LI Min, director of the Office of Global Engagement, and Prof. YANG Geng, vice dean of the School of Mechanical Engineering. This is t...
Macrophage-evading and tumor-specific apoptosis inducing nanoparticles for targeted cancer therapy
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2022-06-29
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In the past decade, nanodrugs have shown considerable advances for cancer therapy. However, despite the successful application of several nano-formulations, most nanodrugs failed for clinical translation due to their insufficient tumor accumulation, and consequently, compromised anticancer efficacy. MPS, which formed by resident macrophages in the liver and spleen, has been demonstrated to sequester the majority of administered nanoparticles, leading to impeded delivery of therapeutics to the tu...