New mechanism in CD47 blockade treatment in HCC
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2022-06-15
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China has the highest morbidity of hepatocellular carcinoma (HCC) in the world. For HCC patients in early stage disease, surgical resection is the best treatment strategy, but most patients in advanced stages lose the opportunity for surgery. Due to the limitations of the current targeted drugs Sorafenib and Regorafenib, immune brake point drugs provide a potential treatment for patients in advanced stages. CD47 blockade could be a promising strategy for HCC treatment. Although anti-CD47 mAb (Hu...
Research collaboration between SAHZU and Mass General Brigham kicks off
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2022-06-15
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On May 26, 2500 doctors from the Second Affiliated Hospital, Zhejiang University School of Medicine (SAHZU) attended an educational and informative lecture about clinical study design delivered by Dr. James Megis, Professor of Medicine at Harvard Medical School and Co-Director of the MGH Clinical Research Program’s Clinical Effectiveness Research GroupThe lecture kicked off the exchange and collaboration in clinical research between SAHZU and Mass General Brigham (MGB), one of the United States...
Genome-wide introgression between two sympatric Asian oak species
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2022-06-14
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The genus Quercus, commonly known as oaks, is one of the most evolutionary successful genera in the Northern Hemisphere in terms of species diversity, biomass and distribution range. Oaks can usually live up to a few hundred years and during the long lifespan they exhibit high tolerance to various abiotic and biotic threats. Meanwhile, oaks are also well known for their extensive interspecific gene flow, which is believed well helpful for their wide dispersal. These traits make Quercus an i...
DAV regimen breaks remission records in AML
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2022-06-11
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Acute myeloid leukaemia (AML) is the most common leukaemia in adults and accounts for about 80% of all cases. DA regimen is the standard induction regimen for adult AML, consisting of daunorubicin and cytarabine, also known as the 3+7 regimen. However, only 60–80% patients with acute myeloid leukaemia achieve complete remission with the DA regimen and long-term (5-year) overall survival in adults is less than 50% in most clinical trials. Novel therapeutic regimens with higher complete remission ...
First International Competition on Modern Bamboo Structure Building Design rounds off: ZJUI freshmen cut a striking figure!
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2022-06-10
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The First International Competition on Modern Bamboo Structure Building Design rounded off on May 13th. The ZJUI team, composed of freshmen LI Xinyang, YU Yingying, LE Zhiyuan, and CUI Xiaotong and DONG Siyi (21’, Civil Engineering), clinched the Innovative Design Award with their project “Loft without Autumn”.As part of Z4G, Zhejiang University’s sustainability action plan in response to the UN 2030 Agenda, the competition was organized by Zhejiang University - University of ...
Scientists discover inter-generational “memory” mechanism of diabetes
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2022-06-09
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Symptomatic treatment was commonly used for chronic diseases in the past. For example, diabetes was often treated by controlling the increase of glucose and alleviating various diabetes-induced complications with insulin. However, how to prevent diabetes has remained elusive in the scientific and medical community, and it has become a global research hotspot to find out the origin of the disease for early intervention.Recently, the team led by Prof. HUANG Hefeng from Women’s Hospital at the Zhe...
Dialogue@ZJU: With LI Zirui from College of Energy Engineering
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2022-05-31
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[Message from the editor: LI Zirui, a doctoral student from College of Energy Engineering, is one of the recipients of the 12th “Top Ten Students” of Zhejiang University. Insightful, inventive and industrious, LI strives on his way to a scientist with the commitment to realizing a blueprint with “zero-carbon buildings”. In this dialogue, we will learn more about his growth trajectory as a researcher as well as an innovator.]Q1: Congratulations on your prize-winning. You strikes the...
Conferral of the bachelor degree for the ZJUI Class of 2022
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2022-05-31
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On the morning of May 29, Zhejiang University-University of Illinois at Urbana-Champaign Institute (ZJUI) held a grand ceremony to confer upon the graduating Class of 2022 their degrees on the Haining International Campus of Zhejiang University.Prof. WU Zhaohui, president of Zhejiang University, and Prof. Robert J. Jones, chancellor of the University of Illinois at Urbana-Champaign, delivered welcome remarks in China and in America respectively. Also present at the ceremony were Prof....
Polypeptide-forming 3D culture developed to expand rare human circulating hematopoietic stem/progenitor cells in steady-state blood
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2022-05-31
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Most cells in steady-state peripheral blood (PB) are lineage mature cells, which are differentiated from hematopoietic stem/progenitor cells (HSPCs) residing in the bone marrow (BM) niche. HSPCs are rare in number and hold self-renewal and multi-lineage differentiation potential, regulating the balance and function of various hematopoietic cell subsets in the blood system. Decades of effort have led to successful transplantation of HSPCs (HSPCT) for the treatment of hematopoietic malignancies an...
Strategic risk-based allocation of regulatory resources to effectively improve food safety
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2022-05-27
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According to the WHO’s ‘Estimates of the Global Burden of Foodborne Diseases’ report in 2015, approximately 600 million people (almost one in 10) worldwide fall ill from eating contaminated food annually; about 420,000 of these cases result in death each year. Moreover, the number of cases of illness caused by eating contaminated food continues to grow. As a result of globalized supply chains, food crosses numerous jurisdictions across many different interventions and stages, including p...