ZJU’s “Heritage Ark” is setting sail on the journey of bringing cultural relics to life
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2022-02-28
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At the 7th China International College Students’ “Internet+” Innovation and Entrepreneurship Competition, a Buddha statue from the northern wall of the Guyang Cave in the Longmen Grottoes was “moved” to the exhibition site. A team named “Heritage Ark” from Zhejiang University replicated relics with 3D printing technology and brought them back to life. Since then, those precious Buddha statues perching in caves have been open to the general public.Heritage Ark...
ZJU scientists elucidate novel molecular mechanism of MYBPC3-related hypertrophic cardiomyopathy using human iPSC-CM model
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2022-02-25
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Hypertrophic cardiomyopathy (HCM), characterized by left ventricular hypertrophy and fibrosis, is the most common monogenic cardiovascular disorder with global distribution and diverse clinical spectrum. The disease prevalence has been estimated at approximately 1:500 in the general population and even higher (1 case per 200) when both clinical and genetic diagnoses are taken into accounts. Patients with HCM are predisposed to heart failure, outflow tract obstruction and arrhythmias. The most vi...
Licensing but not fueling: a metabolic enzyme promotes mitosis beyond metabolism
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2022-02-23
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Uncontrolled cell proliferation is a hallmark of cancer. To sustain the ceaseless cell division, cancer cells rewire metabolic pathways in order to provide sufficient nutrient and energy for mitotic progression. Metabolic reprogramming of cancer cells is usually orchestrated by dysregulation of metabolic enzymes. It is generally thought that dysregulated metabolic enzymes contribute to cell cycle progression mainly by providing essential metabolites to meet the cellular needs for biosynthesis an...
Therapeutic potential of opioid agonists in human leukemia
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2022-02-22
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Leukemia, the blood cancer, is a group of hematopoietic malignancies. Many types of leukemia are associated with poor outcome. Unfortunately, during the past a few decades, the first-line leukemia therapy has long been traditional chemotherapy with high cytotoxicity and low selectivity, such as the “7+3” strategy, i.e., a combination of cytarabine and doxorubicin. Also, side effects of such intensive chemotherapies are often severe, especially in elder patients. Therefore, it is in urgent need...
Unraveling correlation of Cd induced metabolic toxicity and diabetes
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2022-02-17
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Diabetes has become the leading metabolic disease threatening human health. Meanwhile, the association between exposure to harmful environmental factors and the occurrence of diabetes has always been a hot spot of public health and environmental medicine.A recent study conducted by Dr. ZHOU Zhou’s lab at the Department of Environmental Medicine, the Zhejiang University School of Medicine elucidated the Cd perturbed metabolomic signature in pancreatic beta cells and human urine. The origina...
Turn brittle mineral into plastic substitute
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2022-02-16
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Plastics bring much convenience to human life by virtue of their flexibility, plasticity, lightness and cheapness, but they also pose a considerable threat to the natural environment owing to their non-degradable bonds that lead to “white pollution”. In recent years, an increasing number of researchers have started to seek new “plastics” as an alternative to traditional petroleum-based plastics.The research findings by Prof. LIU Zhaoming and Prof. TANG Ruikang from the Department o...
Dialogue@ZJU: With Prof. WEN Wu from the International Campus
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2022-02-15
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【Message from the editor: In the previous issues, Dr. SHAO Fangwei and Dr. LIU Zuozhu from ZJUI, and Dr. CHEN Di from ZJE shared their research and teaching at the International Campus. Today, let’s meet Prof. WEN Wu, who joined the Zhejiang University International Business School (ZIBS) as a full-time professor in 2020. He is also a doctoral supervisor of the College of Computer Science and Technology of Zhejiang University and the Secretary-General of the Internatio...
Solar housing project structured by ZJUers lands in the Winter Olympic City Zhangjiakou
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2022-02-12
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What comes to you when talking about the 2022 Winter Olympics? Fast and fierce actions on the slopes? The cute panda mascot Bing Dwen Dwen? The world has gone warm over the Games since its opening. Want to know how ZJUers contributed to the Games? Let’s turn the spotlight on the Solar House, a Demonstration Project in the host city Zhangjiakou jointly designed and built by an international team, Y-Team composed of students and faculty members from the Zhejiang University-University of Illinois ...
Genetic basis for tissue-specific DNA methylation patterns in plants
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2022-02-11
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How does a cell develop into various types of tissues and organs with the same set of genome? Epigenetic modification patterns play a vital role in these processing. DNA methylation, a type of stably inheritable epigenetic modification, which is ubiquitous and conserved in both animals and plants, are essential for gene regulation, transposon silencing and gene imprinting. However, how DNA methylation patterns are regulated has remained obscure in the field of epigenetics.Recently, Assistant Pro...
ZJU develops cool technology for Beijing 2022 Winter Olympics
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2022-02-10
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Surfing and snowboarding have a lot in common in speed, jumping and spinning. Scientific research also reveals that their actual mechanism is also very similar.Based on these similarities, the Center for Chinese Water Sports Development at Zhejiang University, in partnership with Zhejiang University’s Power Machinery & Vehicular Engineering Institute and Hangzhou Dianzi University, develops the cool technology to help the national snowboarding team brace for the Beijing 2022 Winter Oly...