Directed-evolution of translation system for efficient unnatural amino acids incorporation and generalizable synthetic auxotroph construction
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2021-12-14
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The genetic code of all three kingdoms of life is universal and encodes the same 20 natural amino acids for a variety of complex physiological functions. The expansion of the genetic code by incorporating UAAs with diverse functional groups has enabled the synthesis of proteins with enhanced or novel functions, and the construction of UAA-dependent synthetic auxotrophs. However, it is extremely challenging have an in vivo site-specific UAA incorporation system with comparable efficiency and...
Dialogue@ZJU: Dr. Hyeon Jeong Lee, honoree of MIT Technology Review Innovators Under 35 Asia Pacific 2021
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2021-12-13
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[Message from the editor: Recently, Dr. Hyeon Jeong Lee at the Zhejiang University College of Biomedical Engineering & Instrument Science was awarded with the title of MIT Technology Review Innovators Under 35 Asia Pacific 2021. In this interview, she introduced her research and shared her insights into innovation.] Quotes from the interview:- Innovation requires creativity and combination of different disciplines. So that means you need to learn new things and get into new fi...
Seeing is believing: phase transformation in titanium alloys observed at atomic scale
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2021-12-11
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Titanium is an important structural metal. Titanium alloys are widely used in aerospace and biomedical applications, thanks to their light weight, remarkable specific strength, superb corrosion resistance and high heat resistance.Recently, Prof. YU Qian in Prof. ZHANG Ze’ s group at the Center of Electron Microscopy in Zhejiang University led her team in collaboration with Prof. MA En and Prof. ZHANG Wei from Xi’an Jiaotong University and Prof. Long-qing Chen from the Pennsylvania St...
Does more attention necessarily lead to better working memory?
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2021-12-11
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When logging onto a web page, we are often required to enter a randomly generated verification code. To avoid errors, we need to pay sufficient attention to it. However, this code is no longer needed for future scenarios; thus, the information becomes outdated after serving its one-time purpose. How does the brain deal with this type of attended but outdated information? Recently, the research team led by Prof. CHEN Hui at the Zhejiang University Department of Psychology and Behavioral...
An exploration for lung cancer diagnosis and treatment
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2021-12-10
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Lung cancer is one of the leading cancer types for human mortality. Even though different medical interventions, such as chemotherapy, radiotherapy and immunotherapy, have contributed to lung cancer treatment in a great deal, the lack of an early diagnosis leads to poor prognosis and low overall survival rate. Less than 20% of patients survive to 5 years after diagnosis. Standard lung cancer screening methods employing computerized tomography (CT) examination encounter the challenge of distingui...
Zhejiang University and University of Luxembourg inaugurate joint lab to explore interdisciplinary collaboration
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2021-12-09
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On December 6,the inauguration ceremony of Zhejiang University - University of Luxembourg Joint Lab on Advanced Intelligent Systems and REasoning (ZLAIRE) was successfully held online. The event brought together over 30 delegates from both countries.H.E. YANG Xiaorong, Ambassador of China in Luxembourg, praised the positive role of ZLAIRE in her opening remarks, “The joint lab will provide a brand-new platform for both countries to cooperate in interdisciplinary research and teaching, integrat...
A team of dream builders in Jingdong
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2021-12-05
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[Editor’s note: Today marks International Volunteer Day with the 2021 theme: Volunteer now for our common future. Since 2013, 52 postgraduate students of Zhejiang University have traveled to volunteer in high schools in Jingdong Yi autonomous county, southwest China's Yunnan province, 2600 kilometers away from Hangzhou, where the University is located. The Project of Targeted Support to Jingdong by the ZJU Postgraduate Volunteer Teaching Team was selected by China’s Ministry of Educat...
ZJU researchers reveal the gating mechanisms of the two-pore channel AtTPC1
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2021-12-04
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Voltage-gated ion channels (VGICs) are involved in electrical signal transduction and play essential roles in life activities. How membrane potentially drives conformational change at the voltage-sensing domain (S1-S4, VSD) and regulates channel gating is a central theme for voltage-gated ion channels. To elucidate voltage-gating mechanisms, one needs to capture VSD structures in both the activated state and the resting state. In recent years, the research team led by Prof. GUO Jiangtao fro...
New findings on pollen mitotic division through auxin signaling and sugar metabolism pathways in tomato
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2021-12-04
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On November 23, Prof. LU Gang at the Zhejiang University College of Agriculture and Biotechnology and Dr. Xinai Zhao at Heidelberg University co-published an open-access research article entitled “Phytochrome Interacting Factor 3 regulates pollen mitotic division through auxin signaling and sugar metabolism pathways in tomato” in the journal New Phytologist. This study opens up the door for creating hormone-regulated genic male-sterile lines for tomato hybrid seed productio...
Two ZJU professors named CAS and CAE foreign members respectively in 2021
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2021-12-03
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Recently, two Qiushi Chair professors of Zhejiang University, Prof. Hywel Rhys Thomas and Prof. Billie F. Spencer Jr., have been elected as foreign members of the Chinese Academy of Sciences (CAS) and the Chinese Academy of Engineering (CAE) respectively, China’s highest honor for foreign scientists.“Election as a Foreign Member of the CAS is a very great honor. It is undoubtedly one of the highlights of my professional career. I have already benefitted so much from working with so many highly...