Light activated gene delivery nanodot system to enhance osseointegration
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2020-07-27
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Due to poor osseointegration, patients with osteoporosis or diabetes show high risk of implantation, and often require dental implants with improved osseointegration capabilities. Therefore, there is an urgent need to develop implants that promote osseointegration.Cell sheets play a vital role in gene therapies. Nonetheless, gene delivery platforms based on cell sheet technology are restricted to small genes. Low-density lipoprotein receptor-related protein 5 (LRP5) is a representative large gen...
Dialogue@ZJU: With Dr. Imran Haider Shamsi
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2020-07-26
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[Message from the Editor: Recently Dr. Imran Haider Shamsi won the title "My Favorite Foreign Teacher" in 2019. Here he shared some thoughts with Global Communications.]Of course the moments of joy and happiness, I am very much grateful to the service department of foreign experts of the Ministry of Science and Technology, Beijing, People's Republic of China, for conducting such an amazing competition throughout China. No doubt it's an opportunity for all the foreign exper...
Dr. Imran from CAB clinches the title of "My Favorite Foreign Teacher" in 2019
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2020-07-25
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Recently, the 2019 " Foreign teachers and I" national essay competition and competition for "My favorite foreign teacher" activities came to an end. Dr. Imran Haider Shamsi, a full time Associate Professor from the Institute of Crop Sciences, College of Agriculture and Biotechnology (CAB) of Zhejiang University, was selected as "My favorite foreign teacher" in 2019. The candidates for "My favorite foreign teachers" were selected from the whole country...
ZJU scientists fabricate a hybrid nanomedicine for liver cancer
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2020-07-23
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Liver cancer is the seventh most common cancer and its mortality rate is the third highest. In China, approximately 330,000 people die of liver cancer every year, accounting for 42% of the world’s total death toll. Due to the fact that liver cancer is insidious, upon diagnosis, most patients will be found to be terminally ill and therefore lose the prime time of surgical treatment. Thus, comprehensive treatment, including intervention therapy and chemotherapy, offers the only ray of hope t...
Engineered bacterial outer membrane vesicles enhance efficacy of phototreatment for skin cancer
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2020-07-22
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On July 3, the research team led by Assoc. Prof. PENG Lihua and Prof. GAO Jianqing from the Zhejiang University College of Pharmaceutical Sciences published an open-access research article titled “Engineering bacterial outer membrane vesicles as transdermal nanoplatforms for photo-TRAIL-programmed therapy against melanoma” in the Science Advances.Melanoma is a malignant tumor located at the interface of epidermis and dermis and marked by rapid progression, fast relapse, and high...
Plant DNA virus can use host machinary to replicate in its insect vector
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2020-07-20
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Of 1,000-plus known plant viruses, over 75% are transmitted by aphids, whiteflies, leafhoppers and other insects. However, merely a minority of plant RNA viruses have been confirmed to replicate within their insect vectors in addition to their plant hosts so far. Whether plant DNA viruses have also evolved to replicate in their insect vectors has remained elusive. More importantly, there has been a paucity of research regarding the mechanisms employed by plant viruses to cross the kingdom barrie...
Dialogue@ZJU: With Prof. BAI Qianshen about Chinese calligraphy
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2020-07-16
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[Message from the Editor: Chinese calligraphy holds important position in Chinese culture. Recently Prof. BAI Qianshen, an art historian of calligraphy, a calligrapher, dean of the School of Art and Archeaology and director of ZJUMAA, told us his experiences in teaching calligraphy in the US and the stories about his monograph Fu Shan's World: The Transformation of Chinese Calligraphy in the Seventeenth-Century.]Q1:What are the biggest challenges you faced when you taught calligraphy ...
Across-time-zone online urban design course dissertation amid the pandemic
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2020-07-15
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On the evening of June 23, the fourth-year students in the Zhejiang University Department of Architecture gave their presentations on the final project for the course of Themed Design using zoom. The panel of evaluators, including ZJU professors, Prof. Martin Bechthold, director of the Master in Design Engineering (MDE) program and director of the Doctor of Design (DDes) program at Harvard University, Prof. Vito Bertin who is currently in Hong Kong, and Prof. Lorenzo Barrionuevo who is currently...
Elevated temperatures influence soil N cycling in the global scale
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2020-07-14
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The research team led by Prof. XU Jianming from the College of Environmental and Resource Sources published an article entitled “Elevated temperature shifts soil Nitrogen cycling from microbial immobilization to enhanced mineralization, nitrification and denitrification across global terrestrial ecosystems” in the Global Change Biology on July 2, 2020.Our planet is plagued by severe global warming currently. Since the dawn of the 20th century, the average surface tempe...
Key miRNA related to TACE therapy identified for HCC patients
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2020-07-12
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The research team led by Prof. JI Junfang from the Zhejiang University Life Sciences Institute published a research article titled “MiR-125b Loss Activated HIF1α/pAKT Loop, Leading to Trans-Arterial Chemoembolization Resistance in Hepatocellular Carcinoma” in Hepatology on July 1, 2020. This article elaborates on the regulatory role of miRNA-125b-activated hypoxia signaling pathways in contributing to trans-arterial chemoembolization (TACE) resistance, thus providing prospectiv...