RNA m6A modification sensitizes an oncogenic mRNA-Protein complex to heat stress via reverse regulating the fate of its reader
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2022-11-04
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Human papillomavirus (HPV) is one of the four leading carcinogenic pathogens. In addition to causing 97% of cervical cancers, a significant proportion of the neoplasms of anus, vulva, vagina, penis as well as head and neck squamous cell carcinoma are also caused by HPV infection, leading to serious public health concern with substantial economic burden [1].Therapeutic vaccines or gene therapy are thought to be effective in eliminating HPV infection but display relatively low accessibility a...
Time-restricted feeding can alleviate excessive dark-phase sleepiness, ZJU scientists discover
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2022-11-04
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Obesity induced by the high-fat diet (HFD) is a growing epidemic and major health concern. While excessive daytime sleepiness (EDS) is a pervasive symptom of HFD-induced obesity, research findings suggest that reduced wakefulness could be improved by means of time-restricted feeding (TRF). However, the underlying neural mechanisms remain largely obscure.On October 16, Prof. LI Haohong from the MOE Frontier Research Center of Brain & Brain-machine Integration at Zhejiang University and Prof. ...
Slimming and Greening the Chinese Food System
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2022-11-02
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On 29 August 2022, a research team led by Prof. WANG Xiaoxi from the China Academy for Rural Development and School of Public Affairs of Zhejiang University, and Prof. YUAN Changzheng from the School of Public Health of Zhejiang University published a perspective entitled “The triple benefits of slimming and greening the Chinese food system” in the journal Nature Food. The research was carried out in collaboration with Dr. Benjamin Leon Bodirsky and Dr. Christoph Müller at...
ZJU scientists fill the information gap in the process of the ‘molecular arms race’ between coronaviruses and their hosts
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2022-11-02
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Coronavirus has brought about three massive outbreaks in the past two decades. Each step of its life cycle invariably depends on the interactions among virus and host molecules. The interaction between virus RNA and host protein (IVRHP) is unique compared to other virus-host molecular interactions, and has emerged to be a very hot topic in recent studies (Cell. 184: 2394-2411.e16, 2021; Cell Res. 32: 9-23, 2022). These studies provide essential information for a deeper understanding of IVRH...
Dialogue@ZJU:ZJUer voices for SDGs (Episode 2)
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2022-11-01
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[Editor’s Note: This past summer experienced extremely high heat, coupled with more and more frequent droughts and floods. Is this some punishment for over-industrialization? And where are we heading? ZHANG Yuting (Translation, ’23), at the CGTN's program - The Young Speakers, pointed out that we do not live on an isolated island called my world. She called on young people to develop the capacity to handle the technological power appropriately.] Quotes from the presentation: - I find ...
ZJU’s UAD wins ARCASIA Awards for Architecture 2022
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2022-11-01
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Recently, the Awards Ceremony for the ARCASIA Awards for Architecture 2022 was staged in Ulaanbaatar, Mongolia. Building B1 of the Architectural Design & Research Institute of Zhejiang University (UAD) in ZITOWN, designed by the UAD, received a nomination award in the category of public facilities / commercial buildings.The ARCASIA Awards for Architecture is the most prestigious award in the architecture community in the Asian region. It is parallel to the Pritzker Architecture Pri...
Pages of specimen, prints of Qiushi
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2022-10-31
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In the Zhejiang University College of Pharmaceutical Sciences, there is the Herbarium of Medicinal Plants collecting over 5,000 plant specimens of great medical value and historical significance. As William Blake’s beautiful poem goes, “to see a world in a grain of sand, and a heaven in a wild flower.” Today let’s trace Qiushi Spirit from those silent storytellers.Specimen: a world in a wild flowerGathered from regions of mountains, forests and wetlands in Zhejiang Province, the collect...
ZJU scholars develop Zhejiang’s first sustainable roadmap to achieving carbon neutrality
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2022-10-31
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Driven by the “Double Carbon” goals, the research team led by FU Weiqi at Ocean College, Zhejiang University, offers a clear picture of the current situation and key pathways in the fields of “carbon neutrality” in Zhejiang Province. On this basis, the team provides suggestions and directions on how to achieve “carbon neutrality” for Zhejiang Province. Their research findings are published in an article entitled “Sustainable Approaches to Realize Carbon Neutrality in China: A Case Study o...
ZJU scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism
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2022-10-30
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The immune checkpoint inhibitors, including anti-PD-1 and anti-PD-L1 antibodies (αPD-1 and αPD-L1), have revolutionized tumor immunotherapy. Although αPD-1 and αPD-L1 show excellent efficacy in various tumor types, even in patients with advanced tumors, only 10-30% of patients respond to αPD-1 and αPD-L1 therapy due to primary resistance. Extracellular vesicles (EVs) are highly involved in the progression of the tumor. PD-L1+ tumor-derived EVs (TEVs) cause systemic immu...
Dialogue@ZJU:ZJUer voices for SDGs (Episode I)
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2022-10-30
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[Editor’s Note: Our world is facing many global challenges, from poverty to hunger, from climate change to energy crisis, from inequality to digital gap. How can we tackle these urgent problems? What role should young generation play? In this three-episode dialogue, ZJU students voice their own thoughts on Sustainable Development Goals. LIN Weiwei (English, ’23) called on young people to rebuild faith and rewrite the stories of denial to the ones of motivation at the China-Europe-America Youth...