85 trainees from 12 countries, including South Africa, Croatia, Turkey, and Philippines etc., participated in the wound therapist virtual course launched in March 2022 by SAHZU Global Academy. The wound therapist course is totally 800 minutes long, covering over 40 different topics about wound and stoma management. Front-line knowledge and clinical experience about ostomy, wound treatment and nutrition therapy are also shared by SAHZU specialists of Burns, Colorectal Surgery, Gast...

It is not only a strategic course of action in response to climate change but also an inevitable option to promote the building of a community with a shared future for mankind that every nation should achieve peak CO2 emissions to carbon neutrality. As part of the 125th anniversary of Zhejiang University and Global ZJU for Social Good (Z4G), the 1st Asia-Pacific Carbon Neutrality Symposium was successfully held virtually on April 11-12. The symposium was jointly hosted by Zhejiang...

The interaction between tumor cells and cells in the microenvironment is crucial for tumor metastasis. At present, there is an in-depth understanding of paracrine signaling-mediated cell-to-cell interactions in the tumor microenvironment and its role in tumor metastasis. For example, during the progression of gastric cancer, a variety of cytokines, growth factors and extracellular matrix proteins have been reported to promote the progression and metastasis of tumor cells. Clinically, we have not...

Under the patronage of the World Intellectual Property Organization (WIPO), the Swiss Government and City of Geneva, the International Exhibition of Inventions of Geneva (IEIG) was held from March 16 to March 20. Due to the Covid-19, this year’s IEIG went virtual, receiving about 800 inventions from 25 countries and regions.The team led by ZOU Jun from the Zhejiang University School of Mechanical Engineering won a gold medal at IEIG. Their project was about a customized self-healing s...

On April 1, the organizing committee of the 19th Asian Games Hangzhou 2022 unveiled official posters for the Asian Games and the Asian Para Games, one of which is designed by the team led by GUO Junyan, a sophomore at the Zhejiang University School of Medicine.The poster entitled “Hello Future” takes the form of a GIF. “This poster features a smart and futuristic sense of the Asian Games through the lens of spectators rather than athletes. Spectators are able to shift angles with the hel...

Effective combination therapies are urgently needed to treat triple-negative breast cancer (TNBC), which is insensitive to the existing treatment regimens. However, the synergistic potency of traditional small-molecule combinations is limited mainly due to mismatched molar ratios, inconsistent pharmacokinetics, and intratumoral accumulation of individual drugs. Current nanotechnology offers an unparalleled development on advanced combination drug delivery, especially ratiometric drug delivery in...

[Message from the editor: Launched in 2017, the Program in Innovation, Entrepreneurship and Global Leadership (PIEGL) is a two-year English-taught master degree program recruiting international students from universities worldwide. The program is academically rigorous whilst incorporating strong practical elements through enriched student learning and experiential education. It places great emphasis on global leadership by integrating the essence of innovation management and entrepreneurship. Vi...

Kiwifruit flesh exhibits various colors, ranging from green to yellow, red and even purple. In kiwifruit, the red phenotype is the outcome of anthocyanin accumulation. Anthocyanin is one of the widespread pigments in nature and it plays crucial roles in plants and human beings. At present, several MYB transcription factors have been identified as having the potential of synthesizing anthocyanin in kiwifruit, but their specific regulatory functions and mechanisms have yet to be verified. Rec...

The knee joint is the largest and most complex weight-bearing joint in the human body that enables us to stand and carry out our daily tasks. How much do you know your knee? Human body is the most perfect masterpiece of nature, and the knee joint inside human body has a delicate ultrathin layer of osteochondral interface between SOFT cartilage and HARD subchondral bone. In this interface, the sophisticated structures and excellent force transfer properties allow the knee to resist fatigue damage...

The crosstalk between immune cells and tumor cells within tumor microenvironment crucially determines the fate of tumor progression and metastasis. Cancer immunotherapy has brought unprecedented success in clinical benefits for multiple types of cancer by reinvigorating the functions of tumor-infiltrating lymphocytes. However, the majority of patients do not benefit from immunotherapies because of the accumulation of immunosuppressive tumor-infiltrating myeloid cells (TIMs). Emerging evidence in...