Speaker: Vinay TERGAONKAR, Department of Pathology and theDepartment of Biochemistry, Yong Loo LinSchool of Medicine, NUSVenue: ZJE科研楼 2A 203-1Abstract: Over 90% of human cancers attain immortality by transcriptional re-activation of an enzyme called telomerase reverse transcriptase (TERT). While human gem and stem cells transcribe TERT, its expression is transcriptionally silenced in all somatic cells. How and why TERT is reactivated in the vast majority of human cancers remain fundamental unsolved problems in biology. l will present unpublished results which will suggest why TERT is reactivated in human cancers. l will also describe a molecular mechanism which explains how genetic and non-genetic factors, like high iron-(Fe3+), from consumption ofred meat, collude to re-activate this enzyme, thereby explaining a long-standing link between red meat and carcinogenesis. l will also describe the identification of a small molecule inhibitor of this molecular pathway that may be developed using medicinal chemistry for therapeutic use in a large proportion of human cancers where iron-Fe3+) is a key driver.

Speaker: Sunil BaldVenue: Lecture Hall, Zhejiang University Museum of Art and Archaeology (ZJUMAA), Zijingang CampusAbstract:Architecture privileges “grounded-ness”— in how it acknowledges gravity and situates itself in ‘place.’ Central to this grounded-ness is a clear connection to context, whether in the working process of the architect or as an ambition to respond to those who inhabit it. However, studioSUMO has explored floating, and consequently “ungrounded-ness,” in both design and practice. In this lecture, Sunil Bald, co-founding partner of studioSUMO, will discuss designing from a distance, whether in time or space, and how this has led the embrace of floating as a tectonic andmetaphysical condition for both the architectural object and architecturapractice.

Speaker:Igor O. Shaytanov, Russian State University for the Humanities

Venue: Room 201, No. 5 East Teaching Building, Zijingang Campus

Venue: Room 201, No. 5 East Teaching Building, Zijingang Campus

Speaker: Sean Hand, Deputy Pro-Vice -chancellor (Europe) at the University of Warwick

Speaker:Dominic Hand, poet and writer based in the UK

Speaker:Simon Collison, Tsingshan Chair Professor, Zhejiang UniversityVenue: The Golden Hall, Building C, Chengzhang Complex, Zijingang Campus

Speaker: WANG Yongxiang, Chair Professor of Finance, Shanghai Advanced Institute of FinanceVenue: Room 530, No. 7 Chengjun Building, Zijingang Campus