ZJU NEWSROOM

Cross-species cell landscape constructed at single-cell level

2022-09-02

Thanks to high-throughput single-cell RNA sequencing (scRNA-seq), it is possible to construct single-cell transcriptomic atlases at the organic level. For example, cell atlases for vertebrate and invertebrate systems have been successfully generated, such as Human Cell Landscape (HSC), Mouse Cell Atlas (MCA), Zebrafish Cell Landscape (ZCL) and Drosophila embryo. However, most of these studies...

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ZJU scientists decode Xenopus metamorphosis using its single-cell landscape

2022-08-31

On July 26, the research team headed by Prof. GUO Guoji from the Zhejiang University School of Medicine published an open-access article entitled “Cell landscape of larval and adult Xenopus laevis at single-cell resolution” in the journal Nature Communications. They constructed the Xenopus cell landscape (XCL) using Microwell-seq, a self-developed high-throughput single-cell RNA sequen...

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ZJU scientists discovered intracellular regulatory mechanism of TGF-β

2022-08-30

The classical protein secretion pathway considers that the secreted protein can be recognized by the signal recognition granule after the free ribosome synthesizes the signal peptide, and the ribosome is carried to the endoplasmic reticulum by the signal recognition granule to continue the protein synthesis. At the same time, under the guidance of the signal peptide, the newly synthesized protein ...

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Scientists develop a novel catalyst to promote CO hydrogenation

2022-08-29

The research team led by Prof. XIAO Feng-Shou and Dr. WANG Liang from the Zhejiang University College of Chemical and Biological Engineering in collaboration with Prof. ZHENG Anmin’s team from Chinese Academy of Sciences developed a novel catalytic system that can lead to a remarkable increase in the efficiency of coal-to-olefins. This study has important implications for the developmen...

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Featured on cover of Joule: Perovskite cells face severe reverse bias challenges

2022-08-24

[Editor’s Note: As perovskite solar cells are connected together to form a solar module, cells that are shaded in the module, such as by a fallen leaf, can be driven into reverse-bias operation by cells with higher current output. A recent study featured on the cover of the journal Joule shows how perovskite solar cells can face additional challenges beyond those of silicon cells and proposes inn...

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Dynamic alterations in the respiratory tract microbiota of COVID-19 patients

2022-08-24

The rapid outbreak of coronavirus disease 2019 (COVID-19) threatens global health, and some of infected patients are in critical condition. Microorganisms residing in the gut and respiratory tract can alter susceptibility to and the outcomes of infectious diseases. However, the role of respiratory tract microbes and the relationship between respiratory tract and gut microbiomes in COVID-19 remain ...

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Zhejiang University inspires youngsters in response to UN's 2030 Agenda

2022-08-24

The 2022 Zhejiang University (ZJU) SDG Global Summer School, entitled “SDG for a Better Future”, came to an end on Aug 15. Nearly 1,000 talented students from over 350 universities in more than 80 countries and regions participated in the 14-day program, during which they explored solutions to six of the United Nations’ Sustainable Development Goals (SDGs) through challenging academic modules a...

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Scientists unravel the molecular mechanism of PIN-mediated polar auxin transport

2022-08-22

Auxin is the most important hormone in plants. It is mainly synthesized in cotyledons, young leaves and other growing tissues, and is transported to targeted issues via polar transport to regulate plant development and growth. How is this polar auxin transport (PAT) achieved?The research team from Zhejiang University Recently, the Zhejiang University-Hubei University joint team led by Dr. GUO...

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Dialogue@ZJU: With the members of ZJU Green Origin Association

2022-08-22

[Editor’s note: Established in 1999, the Green Origin Association (GOA), a five-star student association at ZJU organizes various activities on and off campus to raise people’s awareness of environmental protection: birdwatching and bird protection, water protection, garbage collection, public lectures on the SDGs, etc. Recently the association won the UN PRME Award for their excellent perf...

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Nanorods overcome tigecycline resistance of Klebsiella pneumonia

2022-08-19

Long-term and excessive use of antibiotics has caused the spread of antibiotic resistance. The time- and cost-consuming process of new antibiotic development results in the much slower emergence of new antibacterial drugs than that of bacterial resistance. The emergence of superbugs has been growing to become a dominant challenge in human health. Tigecycline is regarded as the last line of defense...

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Zhejiang University Unicorns and Future Unicorns Alumni Startups List 2022 released

2022-08-19

In celebration of the 125th anniversary of Zhejiang University, the Zhejiang University Technology Venture Program, which supports alumni entrepreneurship, jointly released the Zhejiang University Unicorns and Future Unicorns Alumni Startups List 2022 with Ofound Angeland Weilian. The List shows that as of 31 May 2022, ZJU alumni have founded25 uni...

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ZJU scientists identify O-GlcNAcylation as cause of pancreatic tumor growth by regulating MDH1

2022-08-18

Pancreatic cancer is an exceedingly malignant tumor in the digestive system, and its five-year survival rate is little more than 10%. Metabolic alterations are one of the hallmarks of tumor cells. Oncogenic Kras-activated pancreatic ductal adenocarcinoma (PDAC) cells depend heavily on an unconventional glutamine (Gln) catabolic pathway to sustain cell growth. In the conventional pathway, Gln is fi...

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ZJU scientists discover new mechanism for heterochromatin establishment and transcriptional silencing in Magnaporthe oryzae

2022-08-10

Rice is one of the most important crops in the world, particularly in China. The rice yield is most severely hindered by Magnaporthe oryzae. According to the National Agro-Tech Extension and Service Center, approximately 400 acres of rice will be plagued by rice blast in 2022. Therefore, it is of supreme importance to reveal the pathogenic mechanism of Magnaporthe oryzae and discover potentia...

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Perovskite: new LED technology surpasses the lifetime milestone

2022-08-09

Perovskite LEDs are an emerging technology for next-generation display, lighting and communications. While perovskite LEDs can be produced simply at low cost, they show clear technological advantages. They offer the light weight and flexibility comparable to OLEDs, and color purity and tunability similar to LEDs based on III-V semiconductors. With only a few years of research by scientists around ...

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