ZJU scientists develop macromolecular drug for cancer therapy via extracellular calcification2021-02-25Cancer is one of the leading causes of mortality. Chemotherapy is still the most commonly used treatment for cancer patients. It typically relies on drug endocytosis and inhibits tumor cell proliferation via intracellular pathways. However, most chemotherapy drugs damage normal cells since they work by affecting the physiological processes of cell proliferation. The side effects of systemic chemot... READ MORE |
ZJU scientists discover new mechanism of HBV-ACLF2021-02-24Acute-on-chronic liver failure (ACLF) develops in patients with chronic liver diseases, regardless of the presence of cirrhosis and represents the common final pathway leading to death. The short-term mortality rate amounts to 50-90% due to the fact that the cause of hepatocyte injury and the pathway involved in ACLF progression remain elusive. The chronic liver failure (CLIF) Consortium Acute-On-... READ MORE |
ZJU scientists report advances in hepatocellular carcinoma2021-02-23China is a country with a high incidence of liver cancer. According to the Global Cancer Report, the number of liver cancer cases in China accounts for 46.7% of the total number of cases all over the world. Although appreciable progress in the treatment of HCC has occurred over the past few years, current therapeutic effects are far from satisfactory, and the 5‐year survival rate varies from 14% t... READ MORE |
Insect transmission of plant single-stranded DNA viruses2021-02-19Of the approximately 1,200 plant virus species that have been described to date, nearly one-third are single-stranded DNA (ssDNA) viruses, and all are transmitted by insect vectors. It is therefore of immense significance to investigate the insect transmission of plant ssDNA viruses.In January, Prof. WANG Xiaowei from the Zhejiang University College of Agriculture and Biotechnology co-pu... READ MORE |
ZJU scientists reveal transcription activation by a sliding clamp2021-02-18For decades, transcription of bacteriophage T4 late genes has served as a model system to investigate mechanisms of transcription regulation. The T4 late promoters consist of a -10-like element placed at the position corresponding to the bacterial promoter -10 element. Nevertheless, there is no sequence conservation at the position corresponding to the bacterial promoter -35 element. In recent yea... READ MORE |
Happy Chinese New Year2021-02-12To the ZJU community and our international friends, Warmest greetings from the Office of Global Engagement for a Happy Chinese New Year! 2021 is a year of the Chinese zodiac sign “Ox”, starting from Feb. 12th, 2021 and ending on Jan. 31st, 2022. The Ox has long been a symbol of power in Chinese culture. An Ox year is usually considered to be more hopeful and fruitful. May th... READ MORE |
Dialogue@ZJU: What are your plans for Spring Festival?2021-02-11[Message from the Editor: Spring Festival, also known as Chinese Lunar New Year, is an important occasion for the family reunion, and falls on Feb 12 this year. But due to the pandemic prevention, some students have chosen to stay put during the holiday. Some of them share their holiday plans with us.] Emaithy Samudio, Panama, an undergraduate student at the ZJU Ocean College“I have bee... READ MORE |
Decoding personal biotic and abiotic airborne exposome2021-02-08Human diseases are caused by the interplay between intrinsic molecular dynamics and environmental exposures, which can be broadly defined as biological, chemical, physical and even psychological exposures. Abnormal environmental exposures, especially during early life, can lead to a variety of acute and chronic diseases, including cancer, allergy/asthma and autoimmune diseases. The ‘exposome’ wa... READ MORE |
Researchers uncover seed microbiome-mediated disease resistance in rice2021-02-07Prevalence of seed-borne bacterial diseases poses a severe threat to rice production due to a drastic rise of toxin-producing Burkholderia pathogens, which lead to destructive damage to yield, quality and even resilience of paddy ecosystem. Manipulating disease resistance of the host plant is deemed to be a promising alternative and a more environmentally friendly approach in modern agricultu... READ MORE |
Zero to one: at the cutting-edge of research2021-02-02“I attach immense importance to the breakthrough from 0 to 1 and strive relentlessly to pursue innovation and transcendence, which is a driving force for my constant efforts in the cutting-edge research,” said ZHU Yongqun, a recipient of the 16th China Youth Science and Technology Award.ZHU Yongqun has long been committed to research into dangerous disease-inducing bacteria. He has achieved... READ MORE |
Scientists identify the structure of adhesion GPCR–G complexes2021-01-31Recently, the research teams led by ZHANG Yan from the Zhejiang University School of Medicine and Zhejiang Laboratory for Systems & Precision Medicine, SUN Jinpeng from Peking University and Shandong University, and H. Eric Xu from the CAS Shanghai Institute of Materia Medica co-published an article entitled “Structures of glucocorticoid-bound adhesion receptor GPR97-Go complex... READ MORE |
Scientists create single-cell deep-immune atlas of COVID-19 and discover its immunopathology2021-01-30As COVID-19 has been raging across the globe in the past year, it has not only constituted tremendous hazards to the safety and well-being of human beings but also incurred immeasurable economic losses. Although most of COVID-19 patients remain asymptomatic or experience only mild symptoms, about 20% suffer overt pneumonia and roughly 5% cases progress to life-threatening Acute Respiratory Distres... READ MORE |
ZJU4H “Mobile Digital Hospital” ushers in an era of “zero distance” mobile health2021-01-29Imagine that in the future, a “mobile hospital” bus complete with necessary medical equipment will make it to your neighborhood on time as long as you click the “reservation” on your mobile phone.On January 23, the 5G “Mobile Digital Hospital” built by the Fourth Affiliated Hospital of the Zhejiang University School of Medicine (ZJU4H) was officially launched. It is the first “mobile hospit... READ MORE |
Scientists reveal novel mechanism for different parasitic strategies among parasitoid species2021-01-28The research team led by Prof. CHEN Xuexin from Zhejiang University College of Agriculture and Biotechnology and the research team led by Prof. ZHAN Shuai from Chinese Academy of Sciences co-published a research article entitled “Two novel venom proteins underlie divergent parasitic strategies between a generalist and a specialist parasite” in Nature Communications, revealing the novel mechanism... READ MORE |