GPRC5D-targeted CAR T cells show efficacy in phase 1 trial of relapsed/refractory multiple myeloma2023-03-14Multiple myeloma is a malignant disease characterized by the proliferation of clonal plasma cells in the bone marrow. While numerous advances in treatment, such as proteasome inhibitors, immunomodulatory drugs, and monoclonal antibodies, have significantly improved patient survival over the years, the disease remains incurable. Novel immunotherapies, particularly chimeric antigen receptor (CAR) T-... READ MORE |
ZJU scientists establish the world’s first Geminiviridae-Plant-Insect database2023-03-13Prof. ZHOU Xueping and Prof. LI Fei from the Zhejiang University College of Agriculture and Biotechnology led their team to publish their latest work on the world’s first Geminiviridae-Plant-Insect database (GPIBase) in the journal Molecular Plant on February 21. This database serves as a vast reservoir containing comprehensive information about geminivirus genes, plant hosts, inse... READ MORE |
A quantum playground for exploring light topology2023-03-12A new device offers a glimpse into various topological phenomena exhibited by quantized light, advancing the knowledge for building quantum computers.A quantum device fabricated by Zhejiang University researchers could help to advance the design of quantum computers as it offers topological control over the units that store information within them. Their results were published in Science in D... READ MORE |
Why can eating fish make us smarter?2023-03-10When we speak of fat in food, we will easily associate it with its negative effect of “gaining weight”. However, one type of fat has a “weight-losing” effect – it is omega-3 fatty acids. Not only can omega-3 fatty acids reduce fat, but they can also strengthen the brain, regulate the blood pressure, and ease inflammation. Therefore, they can be found in many health products and infant formula ... READ MORE |
Prof. FANG Xiangming: National March 8 Red Banner Pacesetter in 20222023-03-08The 2022 Award for the March 8 Red Banner Holders, Pacesetters and Collectives was unveiled recently. Prof. FANG Xiangming at the Zhejiang University School of Medicine won the March 8 Red Banner Pacesetter award.As a healthcare provider, researcher and educator, FANG Xiangming has long been committed to the world’s scientific and technological frontier, the main economic battlefield, major natio... READ MORE |
Herpesviridae reactivation in the lungs of critical care patients2023-03-06Severe pneumonia is a leading cause of death in the intensive care unit (ICU) and it is frequently accompanied by viral reactivation during treatment. Nevertheless, there have been limited studies that have assessed the viral reactivation patterns in the lower respiratory tract and its impact on the mortality of ICU patients with severe pneumonia.In January 2023, Dr. FANG Xueling and Dr. CAI Hongl... READ MORE |
FAHZU shares experience in treating a patient who has aspirated cement slurry2023-03-05Aspirated cement is a rare and serious safety incident that can have severe consequences. Cement aspiration can lead to the solidification of the airway, compromising lung function and ventilation, and the effective treatment of critically ill patients remains uncertain.Dr. CAI Hongliu’s team from the Department of Critical Care Medicine at the First Affiliated Hospital, Zhejiang University Schoo... READ MORE |
Influenza trains alveolar macrophages to fight cancer2023-03-04The lung is exposed to a variety of respiratory viruses such as influenza, and is also a frequent target organ of both primary and metastatic cancers. Respiratory viral infection was previously shown to induce immunological training of lung tissue-resident alveolar macrophages (AMs) with enhanced anti-bacterial functions. It is however not clear whether previous training experience of AMs by respi... READ MORE |
Insight@ZJU: Universities address climate governance – but barriers remain2023-03-01[Editor’s Note: As climate change continues to be a global issue, what role can top universities play in the climate governance? What obstacles will they face? KAN Yue, professor and director of the UNESCO Research Center at Zhejiang University, DUAN Shifei, associate professor at UNESCO Research Center, and WU Qian, a master’s degree candidate, shared their insights in University World News.]&n... READ MORE |
A positive feedback loop between cancer cells and macrophages drives gastric cancer liver metastasis2023-03-01Metastasis is a major cause of death for gastric cancer patients. The liver is the most common site for distant metastasis of gastric cancer. However, the mechanisms underlying gastric cancer liver metastasis remain largely unknown and the clinical treatment options are very limited. Therefore, it is in urgent need to systematically identify liver metastasis-related genes and discover new therapeu... READ MORE |
Impact of ageing on agricultural sustainability in China: ZJU scientists offer solutions2023-02-28According to the National Bureau of Statistics, approximately one in every five people in China is over 60 years old. This demographic shift towards an ageing population is posing great challenges on agriculture sector. A new study has quantified the impact of ageing through a set of data science research, providing the first explanation of the role of ageing in agriculture and solutions to addres... READ MORE |
Scientists reveal the pathogenic mechanism of peripheral neuropathies2023-02-24Charcot-Marie-Tooth diseases (CMT) are a group of inherited peripheral neuropathies with a prevalence of ~1:2500. According to various causal genes, CMT can be classified into many different subtypes. Despite similar clinical presentation among different CMT2 subtypes, their causal mutant proteins are highly varied in their cellular localizations and functions. It remains unclear whether there is ... READ MORE |
ZJU scientists discover the positive buffering effect of forest edges on plant-pollinator networks in face of declining forest area2023-02-23The decline of insect pollinators has captured immense attention worldwide. Popular notion has it that habitat fragmentation and ecosystem decay exacerbate the decline of insect pollinators due to habitat loss. However, the study conducted by Prof. DING Ping’s team at the Zhejiang University College of Life Sciences found that in forest ecosystems, open sunny forest edges are able to support... READ MORE |
Are people with high social status more prone to depression?2023-02-22Alpha is the “king” of a horde of mice. While meeting another mouse in the pipeline, Alpha can scare it away with merely a glance. But one day the situation changes. With unexpected courage, the little “mouse brother” pushes Alpha out of the way directly after confronting the “king” for several seconds. After experiencing the Waterloo for several successive days, Alpha becomes depressed and ... READ MORE |