Three ZJU scientists selected into New Cornerstone Investigator Program2023-01-15The New Cornerstone Investigator Program, an independent non-profit funding initiative guided by scientists, funded by Tencent and supervised by the China Association for Science and Technology, unveiled its first batch of new cornerstone investigators on January 13. The Program adopts a forward-thinking approach to encouraging basic research spearheaded by leading scientists. Tencent pledges to p... READ MORE |
Positive allosteric modulator targeting TRPV1 for long-lasting analgesia2023-01-13The transient receptor potential vanilloid (TRPV1) ion channel is a polymodal nociceptor broadly expressed in sensory neurons involved in pain sensation, thereby playing an essential role in analgesia. The outer pore domain of TRPV1 is essential for regulation of this channel by temperature, protons and other toxin peptides, so rationally engineering modulators targeting the outer pore of TRPV1 is... READ MORE |
8 books to read over winter holiday2023-01-13[Editor’s Note: Do you what to curl up with a good book as the winter holiday begins? Are you looking for new insight for the new year? It’s a moment to take a breath and consider the past, present and future after the exam week. Here are recommendations from Class of 2022.]Cognitive Awakening by ZHOU LingIt can answer many of my doubts during my freshman and sophomore years. High school li... READ MORE |
Dr. SHI Ye: Continuing ZJU’s legacy of seeking truth2023-01-13[Editor’s Note: Dr. SHI Ye, Assistant Professor at ZJUI, obtained his BS and MS degrees in Polymer Science and Engineering from Zhejiang University under the supervision of Prof. CHEN Hongzheng. He then received his Ph.D. in Materials Science and Engineering from the University of Texas at Austin under the supervision of Prof. YU Guihua. Before joining ZJUI, he worked as a postdoctoral researcher... READ MORE |
Researchers invented the unmanned aerial vehicle-mediated first aid for rapid drug delivery to targeted emergency patients2023-01-12For patients suffering from sudden illnesses such as myocardial infarction and severe hypoglycemia, prompt administration of emergency medications is imperative, otherwise they may be at great risk of death. Actually, a large number of deaths still occur due to untimely emergency care caused by the lack of emergency equipment and therapeutics around the patients, or the inability of the patient to... READ MORE |
Prof. DU Zhenhong leads the development of DDE Platform2023-01-12The Deep-time Digital Earth (DDE) Platform (Deep-time.org 1.0 Alpha), led by Prof. DU Zhenhong at the Zhejiang University School of Earth Sciences, was officially launched on November 8, 2022. Prof. Jennifer McKinley, president of the DDE’s Governing Council, announced this exciting news in the presence of nearly 50 participants attending the meetings of the Governing Council (GC) and t... READ MORE |
New mechanism of glucose starvation-induced autophagy2023-01-05Substance metabolism and energy metabolism are two basic characteristics of life activities. Autophagy is also regulated by substance and energy metabolismand in turn participates in regulating them. So far, the molecular mechanism of substance metabolism regulating autophagy is relatively clear. Autophagy can be induced by amino acid starvation, nitrogen source starvation, growth factor depr... READ MORE |
Dialogue@ZJU: With TANG Mengxia, recipient of the Chu Kochen Scholarship2023-01-05[Editor’s note: Set up in 1986, Chu Kochen Scholarship is the highest honor for ZJU students. TANG Mengxia, among 12 undergraduate students and 12 graduate students, is a recipient of Chu Kochen Scholarship for academic year 2021-2022. An undergraduate as she is, Tang has become a rather experienced researcher, who holds the ambition to trace back by thousands of years to discover the origin of C... READ MORE |
ZJU scientists unlock the "code" of energy transmission across species2023-01-05Spinach has left deep childhood memories for many post-70s and post-80s generations because of the cartoon image of Popeye. Apart from appearing on our table as usual, it is truly endowed with the expectation of great power by scientists. The team of Dr. LIN Xianfeng and Prof. FAN Shunwu, from the orthopedics of Sir Run Run Shaw Hospital (SRRSH), Zhejiang University School of Medicine, and th... READ MORE |
ZJU scientists develop multi-fidelity modeling for pKa prediction2023-01-03Acid-base dissociation constant (pKa), a key physicochemical parameter describing the ionization ability of molecules, plays a vital role in chemical, environmental, agricultural, and medical sciences. In drug discovery, pKa determines the ionization states of drug-like molecules in the physiological environment, thus affecting a wide range of biopharmaceutical properties.Graph Neural Network... READ MORE |
2022: year in review2022-12-312022 was undoubtedly a year of many challenges and changes, but it was also a year of great achievement.We released ZJU’s refreshed global strategy in June, seeking to maximize the university’s impact on the world stage, joined hands with our global partners to launch the inaugural SDG Global Summer School in August, which attracted nearly 1,000 outstanding students from more than 80 countries a... READ MORE |
Structural and biochemical characteristics of mRNA nanoparticles determine anti–SARS-CoV-2 humoral and cellular immune responses2022-12-31The COVID-19 outbreak in 2019 has had a huge impact on global public health. The outbreak meanwhile has also promoted the development and application of vaccine platforms, especially those based on mRNA lipid nanoparticles. However, the mode and difference in role of different mRNA nanocarriers in the induction of antiviral humoral immunity and cellular immunity is still not systematically underst... READ MORE |
ZJU scientists achieve large-depth three-photon fluorescence imaging of cortical microvasculature on nonhuman primates with bright AIE probe in vivo2022-12-31Scientists at Zhejiang University, including Prof. XI Wang and Prof. Anna Wang Roe at the Interdisciplinary Institute of Neuroscience and Technology and Prof. QIAN Jun at the College of Optical Science and Engineering, utilize a bright aggregation-induced emission (AIE) probe to achieve a large-depth three-photon fluorescence imaging of cortical microvasculature on nonhuman primates... READ MORE |
ZJU scientists discover the key roles of hexokinase 2 in shaping microglial functions2022-12-29On December 20, the research team led by Prof. GAO Zhihua and Prof. DUAN Shumin at the Zhejiang University School of Brain Science and Brian Medicine published an open-access research article titled “Dual roles of hexokinase 2 in shaping microglial function by gating glycolytic flux and mitochondrial activity”.Microglia, the primary immune cells and key guardians of brain activity... READ MORE |